Abstract:In order to provide scientific basis for the prevention and control of leptospirosis, the epidemic characteristics of leptospirosis in Guizhou Province from 2010 to 2014 were analyzed using descriptive epidemiological methods. Leptospire isolation and serological detection of leptospirosis patients were performed. The murine rodents’ distribution and density were analyzed using Trap-night method. Results showed that 73 cases of leptospirosis, with 10 death cases, were reported in Guizhou Province from 2010 to 2014. Most of the epidemics occurred in the Southeast of Guizhou Province, accounting for 71.23% (52/73). The peak incidence distributed from June to September of every year. The incidence of the population is mainly farmers, accounting for 69.86%. Seven out of eighteen blood samples of leptospirosis suspected patients were anti-Leptospira iterohaemorrahgiae serogroup antibody positive and no Leptospire was isolated from the leptospirosis suspected patients. The 6 750 traps were placed and 646 murine rodents were trapped. The murine density was 9.57% (646/6 750) and Apodemus agrarius density was on the increase. The 56 strains of leptospires suspected strains were isolated and all of them were isolated from Apodemus agrarius. Species specific PCR identified all the 56 strains as Leptoapire. Serogroup specific PCR further identification showed them were iterohaemorrahgiae serogroup L. interrogans. Our results showed that most of the leptospiro sis epidemics occurred in the southeast of Guizhou Province from 2010 to 2014. Incidences mainly distributed between June and September. The incidence of the population is mainly farmers and Apodemus agrarius were the main murine carrier of leptospire. The Leptoapira serogroup were iterohaemorrahgiae and it was consistent with the serological detection results from patients, which indicated the correlation of murine carrier of leptospire with human leptospirosis epidemics.
基金资助:国家自然科学基金项目(No.81260250、No.81401679); 贵州省优秀青年科技人才培养对象专项资金项目黔科合人字(2015)09号)及贵州省高层次创新型人才培养项目经费(Qian Ke He (2016)4021)和贵州省传染病人才培养基地项目(黔人领发〔2013〕15号)联合资助
作者简介: 李世军,Email:zjumedjun@163.com
引用本文:
刘英, 陈峥宏, 李世军, 姚光海, 黄荷, 马青, 周敬祝, 唐光鹏, 王定明. 贵州省2010-2014年钩端螺旋体病流行特征分析[J]. 中国人兽共患病学报, 2016, 32(11): 1034-1038.
LIU Ying, CHEN Zheng-hong, LI Shi-jun, YAO Guang-hai, HUANG He, MA Qing, ZHOU Jing-zhu, TANG Guang-peng, WANG Ding-ming. Epidemic characteristics of leptospirosis in Guizhou Province from 2010 to 2014. Chinese Journal of Zoonoses, 2016, 32(11): 1034-1038.
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