Abstract:Human avian influenza A(H7N9) virus cases were reported in five epidemic periods continuously in Zhongshan City, Guangdong Province since Jane 2014. To analyze the epidemiological and clinical characteristics of reported human avian influenza A(H7N9) virus cases in Zhongshan City. We analyzed the 15 case investigation data of those human avian influenza A(H7N9) virus cases who lived in Zhongshan City from Jane 2014 to May 2018. Three girls, who were under 3 years, had upper respiratory tract infection with a good prognosis. Twelve adult cases, aged 34-78 years (median 54 years), with male accounted for 58.3% (7/12). All the adult cases developed serious pneumonia symptom, such as difficult breathing and serious hypoxemia, and got ventilator assisted ventilation therapy. Four cases (26.7%) died, among whom 3 were above 50 years with hypertension. The onset time of 60.0% (9/15) cases concentrated from late Jane to early February. The probable route of transmission of 10 cases were through direct contact of live poultry, among which 6 cases bough live poultry from markets to home and butchered themselves. Two cases that had exposed to live poultry markets with no direct contact with live poultry might be transmitted through live poultry market air. Three clusters were identified but human to human transmission couldn?t be ruled out in 2 clusters. Results indicated that in epidemic season of human H7N9 infection, especially the peak period from late Jane to early February, comprehensive measures should be taken to reduce the high risk behavior, including purchase live poultry from markets and slaughter of live poultry among residents, especially those aged 50 years and above with basic disease in Zhonghan City.
王曼, 陈秀云, 罗乐, 毛云霞, 陈雪琴, 李雷. 2014-2018年中山市人感染H7N9禽流感病例特征分析[J]. 中国人兽共患病学报, 2018, 34(10): 961-965.
WANG Man, CHEN Xiu-yun, LUO Le, MAO Yun-xia, CHEN Xue-qin, LI lei. Characteristics of reported human avian influenza A(H7N9) virus cases in Zhongshan City from 2014 to 2018. Chinese Journal of Zoonoses, 2018, 34(10): 961-965.