Abstract:To combat the ongoing pandemic COVID-19, considerable resourances have been devoted to genome around the world the causative agent, SARS-CoV-2. As of June 24th, 2020, more than 55K genome sequences have been aggregated in the EpiCoV database of GISAID web site in less than 6 months, however, genomic epidemiology analysis was challenged by the relatively large genome size and complex coding sequences of SARS-CoV-2. In this review, current progress in genomic epidemiology studies of SARS-CoV-2 was summarized, facilitating professionals to timely understand virus characterization and transmission trends of SARS-CoV-2, make good use of open-source genomic epidemiology platforms to promote the development of vaccines and antiviral drugs, and eventually to suppress spread of this pandemic COVID-19.
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