2014-2019年中山市H9亚型禽流感监测及病例特征分析

doi:10.3969/j.issn.1002-2694.2021.00.013

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (1939 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要目的分析中山市H9亚型禽流感病毒外环境监测情况及人感染H9N2禽流感病例特征,指导H9N2禽流感防控工作。方法 2014-2019年采集监测镇区内的禽类批发市场、活禽销售市场和生鲜禽销售市场3类交易场所的外环境标本进行禽流感病毒核酸检测,并对人感染H9N2禽流感报告病例进行流行病学分析。结果共采集和检测外环境标本9 015份,检出H9亚型禽流感病毒阳性标本2 171份,阳性率为24.08%。阳性率自2015年起呈逐年上升的趋势(趋势χ²=785.258,P<0.001),不同季节均有一定程度流行。监测镇区均有阳性检出,总体阳性率较高的是五桂山、东升、沙溪、东凤、神湾和小榄等镇区。由不具备独立集中屠宰场供货的生鲜禽销售市场的阳性率最高(36.84%,231/627)。鸡与其它禽类混养阳性率增高(28.91%,920/3 182)。采样部位为冰箱等生鲜禽存放器的阳性率最高(32.71%,105/321),其次是笼具(31.27%,491/1 570)。期间报告3例人感染H9N2禽流感病例,均为常规监测所发现。病例发病时间在冬季或夏季,均有活禽暴露史。中山市涉禽环境中普遍存在H9亚型禽流感病毒,不同季节均有流行风险。生鲜上市设置独立屠宰区,禽类单独存养,注重冰箱、鸡笼等的消毒清洁,有助于提高防控效果。强化监测有利于及早发现感染病例。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	陈楚莹
	王曼
	冯志锋

关键词 ： H9亚型禽流感病毒, 人感染H9N2禽流感, 外环境, 监测, 流行病学特征

Abstract：The H9 avian influenza virus environmental surveillance and cases of human infection with H9N2 virus in Zhongshan City from 2014 to 2019 were analyzed in this study. In 2014-2019, environmental samples from wholesale, live poultry and fresh poultry markets in the monitored towns were collected, and nucleic acids of avian influenza virus were detected. Epidemiological analysis was conducted on the reported cases of human infection with H9N2 avian influenza. A total of 9 015 samples were collected, and the positivity rate of the H9 subtype was 24.08%. The rate had been increasing each year since 2015 (trend χ²=785.258, P<0.001), and the prevalence differed by season. All monitored towns had positive detection, and the overall positivity rates were relatively high in Wuguishan, Dongsheng, Shaxi, Dongfeng, Shenwan and Xiaolan. The highest positivity rate was found in fresh poultry markets that did not have independent slaughterhouses (36.84%, 231/627). The presence of chickens with other birds increased the positivity rate (28.91%, 920/3 182). Refrigerators had the highest positivity rate (32.71%, 105/321), followed by cages (31.27%, 491/1 570). Three cases of human infection with H9N2 avian influenza virus were reported, all of which were identified through routine monitoring. All cases involved exposure to live poultry in the winter or summer. The results showed that avian influenza a (H9N2) virus exists in poultry environments in Zhongshan City and poses epidemic risks in different seasons. Setting up independent slaughterhouses for fresh products, keeping birds separately, and emphasizing the disinfection and cleaning of refrigerators and cages would help to improve virus control. Strengthened surveillance would aid in identifying cases of infection.

Key words： H9 subtype avian influenza virus human infection with avian influenza A(H9N2) virus external environment surveillance epidemiology

收稿日期: 2020-07-10

R373

基金资助:中山市社会公益科技研究重大项目(No.2019B1008)

通讯作者: 陈楚莹,Email:48532810@qq.com;ORCID:0000-0001-6553-0182

引用本文:

陈楚莹, 王曼, 冯志锋. 2014-2019年中山市H9亚型禽流感监测及病例特征分析[J]. 中国人兽共患病学报, 2021, 37(2): 122-127. CHEN Chu-ying, WANG Man, FENG Zhi-feng. Surveillance and case characteristics of H9 subtype avian influenza in Zhongshan City, 2014-2019. Chinese Journal of Zoonoses, 2021, 37(2): 122-127.

链接本文:

http://www.rsghb.cn/CN/10.3969/j.issn.1002-2694.2021.00.013 或 http://www.rsghb.cn/CN/Y2021/V37/I2/122

[1] Chang H, Peng L, Chen L, et al.Avian influenza viruses (AIVs) H9N2 are in the course of reassorting into novel AIVs[J]. J Zhejiang Univ Sci B,2018,19(5):409-414.2018, 19(5):409-414. DOI:10.1631/jzus.B1700374
[2] 曾志笠,傅伟杰,刘晓青,等.H9N2 禽流感病毒相关性新型人感染禽流感研究进展[J].中国公共卫生,2017,33(5):845-848. DOI: 10.11847/zgggws2017-33-05-42
[3] 辛丽,舒跃龙.潜在的流感大流行病毒: H9N2禽流感病毒[J].中华实验和临床病毒学杂志,2013,27(3):234-235. DOI: 10.3760/cma.j.issn.1003-9279.2013.03.025
[4] 刘艳慧,李魁彪,李铁钢,等.2018年广州市禽类市场全社区禽流感病毒监测分析[J].国际病毒学杂志,2019,26( 3 ): 149-152. DOI: 10.3760/cma.j.issn.1673-4092.2019.03.002
[5] 陈修邓,陆巧芬,冯开容,等.江门部分活禽批发市场休市前中后的禽流感病毒核酸监测与分析[J].广东畜牧兽医科技,2017,42(2):30-31. DOI: 10.3969/j.issn.1005-8567.2017.02.007
[6] 张雪宝,陈泽玲,倪锡河,等.珠海市禽类市场禽流感病毒污染控制研究[J].中国预防医学杂志,2018,19(10):742-746. DOI:10.16506/J.1009-6639.2018.10.005
[7] 郭元吉,李建国,程小雯,等.禽H9N2 亚型流感病毒能感染人的发现[J].中华实验和临床病毒学杂志,1999,13(2): 5-8. DOI:10.3760/cma.j.issn.1003-9279.1999.02.001
[8] Pepin KM, Wang J, Webb CT, et al.Multiannual pattens of influenza A transmission in Chinese live-bird market svstems[J].Influellza Other Respir Virus,2013,7(1):97-107. DOI:10.1111/j.1750-2659.2012.00354.x
[9] 刘慧,陈宗遒,肖新才,等.广州地区活禽市场休市措施对控制禽流感病毒污染效果的评价[J].中华流行病学杂志,2014, 35(7):832-836. DOI: 10.3760/cma.j.issn.0254-6450.2014.07.017
[10] 黄朝华,饶贵平,邹喆,等.贺州市2010年-2015年禽流感环境监测结果分析[J].中国卫生检验杂志,2016,26(18):2697-2699.
[11] 刘晓青,曾志笠,傅伟杰,等.江西省2015-2016年活禽市场禽流感监测分析[J].中华疾病控制杂志,2018,22(2): 161-164. DOI: 10.16462/j.cnki.zhjbkz.2018.02.014
[12] 郑丽兰,张海冰,陈裕,等.广州市农贸市场家禽生鲜上市政策实施效果评估[J].中国动物检疫,2017,34(1):4-7. DOI: 10.3969/j.issn.1005-944X.2017.01.002
[13] 张如胜,姚栋,叶文,等. 2014年长沙市禽类场所环境H9N2亚型禽流感病毒分子流行特征分析[J].中国人兽共患病学报,2017,33(3):212-221. DOI: 10.3969/j.issn.1002-2694.2017.03.005
[14] 谢朝军,苏文哲,李魁彪,等,禽类生鲜上市减少市场环境禽流感病毒污染的研究[J].中华流行病学杂志,2016,37(3):353-357. DOI: 10.3760/cma.j.issn.0254-6450.2016.03.012
[15] 杨磊,杜训波,张晓春,等.成都市首例人感染H9N2禽流感病例调查与分析[J].中国人兽共患病学报, 2017,33(3):245-249. DOI: 10.3969/j.issn.1002-2694.2017.03.010
[16] 游胜,冯秀,刘晓青,等.江西省首例人感染H9N2 禽流感病例流行病学调查[J].现代预防医学,2017,44(5):782-784. DOI: CNKI:SUN:XDYF.0.2017-05-004
[17] 康敏,钟豪杰,黄国锋,等.广东省人感染禽流感疫情流行病学特征分析[J].华南预防医学,2015,41(4):323-327. DOI: CNKI:SUN:GDWF.0.2015-04-007
[18] 陈宗遒,陆剑云,肖新才,等. 广州地区2006-2012年人感染H5/H7/H9亚型禽流感病毒风险监测[J]. 中华流行病学杂志,2013,34(9):900-905. DOI: 10.3760/cma.j.issn.0254-6450.2013.09.010
[19] Wang Q, Ju L, Liu P,et al.Serological and virological surveillance of avian influenza A virus H9N2 subtype in humans and poultry in Shanghai,China,Between 2008 and 2010[J].Zoonoses Public Hlth,2015,62(2):131-140. DOI: 10.1111/zph.12133