Abstract:To investigate the possible infection sources and risk factors for a highly sporadic epidemic of brucellosis among humans in the main urban area of Suzhou from 2016 to 2017, and to provide a basis for prevention and control strategies, a case-control study was carried out according to a 1:4 ratio of cases to controls. A household epidemiological investigation was conducted, and basic information, clinical manifestations and suspected exposure history were collected, blood cultures of confirmed cases were isolated and purified, and strains were analyzed by multi-locus variable number tandem repeat sequence. Among the 33 cases investigated, the highest proportion of exposure, related to mutton, was 97%. The main methods of exposure were use and direct contact, and the main place of exposure was the Fengmen Market. Consumption of mutton, direct contact with raw mutton, and travel to mutton markets and Frengmen Street were risk factors. The 17 strains could be divided into five genotypes by multiple locus tandem repeat analysis, but their genetic relationships were close. The source of the epidemic in the main urban area of Suzhou may be brucellosis infected sheep imported from other places to Suzhou and slaughtered in the urban area of Suzhou or direct imports of infected mutton. Lamb sold in the Fengmen Market is one of the possible sources of infection. In this outbreak, the main route of Brucella infection among non-occupationally exposed people was eating and direct contact with infected mutton, inhaling aerosols from infected raw mutton may also be a route of infection.
包林, 崔加瑞, 陈立凌. 2016——2017年苏州市主城区一起人间布病暴发疫情流行病学调查[J]. 中国人兽共患病学报, 2022, 38(6): 548-552.
BAO Lin, CUI Jia-rui, CHEN Li-ling. Epidemiological investigation of a human brucellosis outbreak in main urban area of Suzhou City from 2016 to 2017. Chinese Journal of Zoonoses, 2022, 38(6): 548-552.