Abstract：Aim To observe the effect of garlicin and minocycline on the cyst formation of T.gondii in mice.Methods Mice infected with T.gondii Fukaya strain cysts by peritoneal injection were divided into groups and treated with garlicin or minocycline and with no treatment in the control.Forty five days later,observed the number of Toxoplasma cyst in the mouse brain.Result Garlicin increases obviously the number of cysts in the mouse brain in acute stage;minocycline killed Toxoplasma tachyzoites and reduced obviously the number of cysts in the mouse brain.After the cyst formation,either garlicin or minocycline had no effect on elimination of cysts.Conclusion It suggests preliminary that garlicin can increase the harvest of cysts and both garlicin and minocycline have no effect on already formed T.cyst.
