Drug resistance and molecular typing of nontyphoid Salmonella of infectious diarrhea in Tai’an City, China
ZHANG Xin-feng1, WANG Lei2, XU Gui-yong3, LI Jing3, HU Bin4
1. Tai’an Center for Disease Control and Prevention, Tai’an 271000,China; 2. Laiwu lenter for Disease Control and Prevention,Laiwu 271000,China; 3. Taishan District Center for Disease Control and Prevention, Tai’an 271000,China; 4. Shandong Center for Disease Control and Prevention, Jinan 250000,China
Abstract:We investigated the serotype, drug resistance features, molecular types, and homology of Salmonella in diarrhea in Tai’an City, and provided scientific evidences for warning, control and clinical treatment. The 31 Salmonella strains isolated from stool specimens of diarrhea in Tai’an were identified by serotyping. Broth dilution technique was used to test the sensitivity of 31 strains of Salmonella to 16 antibiotics. Pulsed field gel-electrophoresis (PFGE) was used for molecular typing and cluster analysis. Results showed that 31 strains of Salmonella were divided into 10 kinds of serotype. S.enteritidis (11/31) was the predominant serotype. All 31 strains of Salmonella were sensitive to cefoxitin and imipenem. The drug resistance rates of the 31 strains of Salmonella were 77.42 % (24/31) to sulfafurazole. The 31 strains of Salmonella were divided into 17 patterns by PFGE, with 100% similarity for each pattern. All the results suggest that there are more serious problems in multiple drug resistance. The genetic variation of S.enteritidis is relatively conservative. Early warning and control on S.enteritidis are exposed to reinforce.
张新峰, 王蕾, 徐贵永, 李静, 胡彬. 泰安市感染性腹泻非伤寒沙门菌耐药监测及分型研究[J]. 中国人兽共患病学报, 2017, 33(4): 337-342.
ZHANG Xin-feng, WANG Lei, XU Gui-yong, LI Jing, HU Bin. Drug resistance and molecular typing of nontyphoid Salmonella of infectious diarrhea in Tai’an City, China. Chinese Journal of Zoonoses, 2017, 33(4): 337-342.
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