Abstract:Chinese scientists have studied oral rabies vaccine (ORV) of dogs since 1980s and conducted mass oral vaccination trials in dogs. Some attenuated strains have been selected. Their attenuated characteristics、immunogenicity and genetic stability have been shown similar to those rabies oral vaccine strains approved by WHO and now widely used in the world. The key measure for elimination of human rabies is to increase the vaccination coverage to 70%, which has been confirmed by WHO and rabies experts. Oral vaccination for dogs is a complementary measure to increase vaccination coverage in mass parenteral dog vaccination campaigns. China has a high population of dogs reached to 100 millions, it is very difficult to reach the dog vaccination coverage to 70% depending on parenteral vaccination only.It is suggested that Chinese government needs to support those promising oral vaccine strains developed by Chinese own scientists for application in China as earlier as possible, and then to achieve the goal of eliminating human rabies by 2030.
俞永新, 石磊泰. 中国狂犬病口服疫苗的研究进展及其应用的紧迫性[J]. 中国人兽共患病学报, 2019, 35(11): 973-980.
YU Yong-xin, SHI Lei-tai. Research progress and urgency of application of oral rabies vaccines for dogs in China. Chinese Journal of Zoonoses, 2019, 35(11): 973-980.
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