Advance on crucial outer membrane proteins of Brucella species
LIU ZHi-guo1, 2, WANG Miao3, CUI Bu-yun1, LI Zhen-Jun1
1. National Institute of Infectious Diseases Control and Prevention, Chinese Center for Disease Control and Prevention/Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, Beijing 102206, China; 2.Inner Mongolia Autonomous Region Central for Comprehensive Disease Control and Prevention, Huhhot 010031, China; 3.Ulanqab Center for Endemic Disease Control and Prevention, Ulanqab 012000, China
Abstract:Brucellosis is an important zoonotic infectious disease of humans and livestock with worldwide distribution and is caused by bacteria of the genus Brucella. Brucellosis not only can result in the greater economic loss, and it was also mainly risk factors to health of human population. Outer membrane proteins of Brucella spp. are mainly immunogen and protective antigen, these proteins not only closely with virulence and intracellular survival of Brucella, but also play a significant role for exploring and establishing the novelty serological diagnosis method. The crucial out membrane proteins of Brucella species were reviewed, in order to understand the antigenic characteristics of protein molecular of Brucella species and provided a reference for brucellosis laboratory diagnosis methods and novelty vaccine research.
刘志国, 王妙, 崔步云, 李振军. 布鲁氏菌重要膜蛋白研究进展[J]. 中国人兽共患病学报, 2019, 35(5): 440-446.
LIU ZHi-guo, WANG Miao, CUI Bu-yun, LI Zhen-Jun. Advance on crucial outer membrane proteins of Brucella species. Chinese Journal of Zoonoses, 2019, 35(5): 440-446.
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