1.Yunnan Institute of Endemic Diseases Control and Prevention, Dali 671000, China; 2.Gucheng District Center for Disease Control and Prenvention,Lijiang 674100,China; 3.Heqing County Center for Disease Control and Prenvention,Dali 671500,China; 4.National Institute for Communicable Disease Control and Prevention, Beijing 102206, China
Abstract：We investigate the primary host animals(rodent) and indicator animals(domestic dog) carrying Yersinia enterocolitica in Apodemus chevrieri and Eothenomys miletus plague foci, and to grasp the ecological distribution characteristics of the Yersinia enterocolitica in the plague natural foci. By isolating Yersinia enterocolitica from samples of rodents and domestic dogs, testing serotype and biotype and virulence gene. Results showed that 43 strains of Yersinia enterocolitica were detected from62 rodent specimens with a carrying rate of 35.5%. The 96 strains of Yersinia enterocolitica were detected from171 dogs specimens with a carrying rate of 26.3%.The 138 strains of Yersinia enterocolitica were biotype 1A.One strain of Yersinia enterocolitica was biotype 3 and serotypeO∶3. In conclusion, the carring rate of Yersinia enterocolitica of rodents were more than domestic dogs. Nonpathogenic Yersinia enterocolitica was the dominant strain. It is important to research the distribution and biological characteristics of Yersinia enterocolitica in the plague foci for disease prevention and control, and it is also helpful to investigate the long-term preservation and variation mechanism and correlation of pathogenic Yersinia in nature.
[1] 景怀琦,徐建国.小肠结肠炎耶尔森菌感染性疾病[J].疾病监测,2005,20(9):449-450. DOI:10.3784/j.issn.1003-9961.2005.09.001 [2] 汪华.小肠结肠炎耶尔森菌[M].北京:人民卫生出版社,2004:2. [3] Wang X,Cui Z,Jin D.Distribution of pathogenic Yersinia entero-colitica in China[J].European J Clin Microbiol Infect Dis,2009,28(10):1237-1244. DOI:10.1007/s10096-009-0773-x [4] Bottone EJ. Yersinia enterocolitica: the charisma continues[J].Clin Microbiol Rev,1997,10:257-276. DOI:10.1128/CMR.10.2.257 [5] Thoerner P, BinKingombe C I, Bogli-StuberK,et al.PCR detection of virulence genes in Yersinia enterocolitica and Yersinia pseudotuberculosis and investigation of virulence gene distribution[J].Appl Environ Microbiol,2003,69:1810-1816. DOI:10.1128/AEM.69.3.1810-1816.2003 [6] Wang X,Qiu H,Jin D,et al. O∶8 serotype Yersinia enterocolitica strains in China[J].Int J Food Microbiol,2008,125:259-266. DOI:10.1016/j.ijfoodmicro.2008.04.016 [7] Singh I, Virdi JS. Production of Yersinia stable toxin (YST)and distribution of yst genes in biotype 1A strains of Yersinia enterocolitica[J].J Med Microbiol,2004, 53:1065-1068. DOI:10.1099/jmm.0.45527-0 [8] 肖玉春,王鑫,邱海燕,等.中国致病性小肠结肠炎耶尔森菌生物分型研究[J].中国人兽共患病学报,2010,26(7):651-653. DOI:10.3969/j.issn.1002-2694.2010.07.009 [9] Nuorti JP, Niskanen T, Hallanvuo S,et al.A widespread outbreak of Yersinia pseudotuberculosis O∶3 infection from iceberg lettuce[J].J Infect Dis,2004,189(5):766-774. DOI:10.1086/381766 [10] 景怀琦,李继耀,肖玉春,等.O∶3和O∶9小肠结肠炎耶尔森菌主要毒力基因分布调查[J].中国媒介生物学及控制杂志,2004,15:317-319. DOI: 10.3969/j.issn.1003-4692.2004.04.024 [11] Mliller VL,Falkow S.Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of epithelial cells[J].Infect Immun,1988,56(5):1242-1248.
2019, Vol. 35 
