Epidemiological investigation of a brucellosis outbreak in Shaanxi Province in 2020
LUO Bo-yan1, NIE Shou-min1, AN Cui-hong1, SUN Yang-xin1, CHANG Wen-hui1, DAI Xian-hong2, FAN Suo-ping1
1. Shaanxi Provincial Center for Disease Control and Prevention, Xi'an 710054, China; 2. Jingyang County Center for Disease Control and Prevention, Jingyang 713700, China
Abstract:The study examined the case of a familial brucellosis outbreak in Shaanxi Province in 2020. After investigation, a total of seven cases and six cases of latent infection were found, which had a relationship between seven cases and two latent infection cases. The blood antibody titer of Brucella, determined through SAT tests, ranged from 1∶100 (++) to 1∶800 (++++) or more. A total of seven cases were found from March 18th to May 7th in 2020, and the main clinical symptom was fever. According to our analysis, beef consumption was not the reason for brucellosis (OR=0.48), and the brucellosis infection correlated with visiting the home of the first case (OR=141.00). Five Brucella strains were isolated from the blood of two cases, two sheep and one male dog, and all strains were B. melitensis type 3. The five Brucella strain gene types were exactly the same as those determined through multiple locus variable-number tandem-repeat analysis: 1-5-3-13-2-2-3-2-4-41-8-6-4-3-4-5. On the basis of our epidemiological investigation and laboratory results, we believe that the family brucellosis outbreak occurred because the male dog was infected with brucellosis through eating the blood products of brucellosis-positive sheep; subsequently, nine families became infected through direct contact with the sick dog, respiratory tract, water polluted by sick dogs and other living environment goods.
罗波艳, 聂守民, 安翠红, 孙养信, 常文辉, 戴先红, 范锁平. 2020年陕西省一起布鲁氏菌病暴发疫情的调查分析[J]. 中国人兽共患病学报, 2021, 37(9): 861-865.
LUO Bo-yan, NIE Shou-min, AN Cui-hong, SUN Yang-xin, CHANG Wen-hui, DAI Xian-hong, FAN Suo-ping. Epidemiological investigation of a brucellosis outbreak in Shaanxi Province in 2020. Chinese Journal of Zoonoses, 2021, 37(9): 861-865.