Abstract：The molluscicidal effect of the plant molluscicide HL to Oncomelania hupensis in laboratory and field investigation.In laboratory experiment,effect of HL was performed by spray,immersion and climbing test to observe the inhibitory effect of HL on the climbing action of snails.The field spray investigation was done in Wuhu of Anhui province by spray with different concentration of HL(40,80 and 120 g/m2;and 50 % of niclosamide powder(2 g/m2)and pure water were used as the drug control and blank control.The surviving condition of snails was examined 3,7 and 15 days after application of medicines.It was found that the 50% lethal concentration(LC50)of HL used in spray method for 24,48 and 72 hours were 269,117 and 65g/m2)respectively,while by using the immersion method,they were 115.4,10.6 and 9.9 mg/L.The 50% effective concentration(EC50)of HL to inhibit the climbing of snails 24 hours after usage of drug was 55.8 mg/L.In addition,the death rate of snails sprayed with 80 g /m2 of HL 15days after spraying was 84%,and that of the immersion method using 40 g/m2 of HL for 3 days was 80%.As to the drug control groups,they were 91% for spray of niclosamide for 15 days and 100% for water immersion for 3 days.From these observations it is evident that plant molliscicide HL has molluscicidal effect on Oncomelania hupensis.
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