Abstract:The pathologic characteristics in spleen and liver of mice infected with Yersinia enterocolitica serotype O∶9 was studied by means of artificial infection method and pathological technology.Three groups of mouse infection models were induced by celiac injecting with different concentration of Yersinia enterocolitica serotype O∶9.The hepatic and splenic sections stained with HE(Hematoxylin and Eosin)were examined for the pathologic changes.Inflammatory reaction was observed at the early stage of infection,denaturation and necrosis were the major characteristics for liver and spleen cells,typical "cat eye" was observed in spleen.The process of spleen is 6 hour later than that of liver.It showed that pathologic changes of Yersinia enterocolitic infection has close correlation with bacteria quantity and time of infection.
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