Abstract:In order to understand the relationship between Toxoplasma gondii infection and the detect of nervous system in feeble intelligence children,a part of this kind of children was chosen for study,and their specific toxoplasma antibodies were detected by means of ELISA and IHA assays 3 and 6 months after treatment with acethyspiramycin.It was demonstrated that the average positive detection rates of the specific toxoplasma antibodies in sera of 18 cases under treatment of 3 and 6 months were 16.67%(3/18) in ELISA and 11.11%(2/18) in IHA,and those of cases without treatment were 6.56%(1/18) both in ELISA and IHA;both of which were higher than those of the normal controls[ 1.96%(1/51) both in ELISA and IDA].The average positive detection rate of feeble intelligence children under treatment was obviously lower than that of cases without treatment.[20.69%(6/29) in ELISA and 21.14%(7/29) in IHA] with a significant difference in statistics(X~(2)=1.54,2.01,P<0.05).From the observations in the present study,it is evident that the toxoplasmosis in children is closely associated with the Toxoplasma gondii infection of mothers during pregnancy or the close contact with animals of these children.Because toxoplasma can damage brain and interfere function and development of nervous system,therefore,the conventional examination of antibodies against toxoplasma in feeble intelligence children is necessary and the effective treatment for the toxoplasma infection is essential in the meantime.