Abstract:To observe the concentration of nitric oxide(NO) and TNFα in cerebrospinal fluid of patient with cerebral cysticercosis,the levels of TNF-α and NO in CSF of 28 patients with neurocysticercosis and 24 healthy people as control were detected by sandwich-ELISA and colorimerty.The level of TNF-α in patients and normal individuals was(0.69±0.11)×10~(-3) ng/L and(0.24±0.09)×10~(-3) ng/L(P<0.01);while that of NO in patients and normal indivivuals were(67.77±5.57)μmol/L and(38.04±4.13)μmol/L respectively(P<0.01).It is concluded that the immune response of patients with cerebral cysticercosis are modulated by TNF-α and NO which could generate inflammatory response and cytoxicity on central nervous system of patients.
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