Abstract：The specific non-free circulating antigen(NF-CAg) of dissociated CIC in sera from 370 cases was detected by ELISA with anti-SEA polyclonal antibody. The cases consisted of acute,chronic and advanced schistosomiasis,cured schistosomiasis,other parasitosis and healthy individuals. The positive rates of acute,chronic and advanced schistosomiasis cases were 76.7%, 80.0% and 60.0% respectively. The NF-CAg level(mean OD values) of this group was higher than those of healthy individuals significantly(P＜0.01). The cross reaction rates with other parasitosis cases were 5.0～10.0% and the false positive rate of healthy individuals was 8.8%. The turned negative rates treated after 3 months, 6 months and 3 years were 86. 7 %,82. 0% and 96.7% respectively,and the NF-CAg levels of all those were approaching or lower than those healthy individuals. The results further showed that the specific NF-CAg of dissociated CIC was possessed of value for the diagnosis and the eveluation of effective chemotherapy.
