Abstract:Contour-clamped homogeneous field electrophoresis was used to separate the chromosome DNAs of 8 Candida species and then the Southern blotting membranes were hybridized w i th total chromosome DN Asof the C.albicans and C.tropicalis,respectively. From the results of the hybridizations, we could see the relations among different species and determine the systemaic statue of the strains tested. The study showed that this method was possessed of good specificity and reliability as a new way of genotype identification.