Studies on Natural active immunity of Epidemic Hemorrhagic Fever (EHF) in Population of Henan ProvinceⅡ. Dynamics of Natural active immunization of ENF in resident of three type epidemic areas
Abstract：This study discovered that the protective antibody in high level in the people of 3 kinds of epidemic areas could be accumulated naturally during EHF was epidemic.When the positive rate of EHF antibody in the crowd was 10000-20000/100000,the epidemic tends to reduce or stop.The result indicated that immunitive barrier in the crowd was already formed naturally.When the immunitive barrier (or balance) was broken due to the gradual reduction of the protective antibody of the crowd and the increase of the number of susceptible persons,the epidemic of EHF would occur again.When the positive rate of the crowds was 10000-20000/100000,the protectively immunitive barrier formed.The titer of effectively protective antibody examined with IFAT was 1:20.Reinfection was not found after 3-5 years in persons infected by EHFV,whatever the EHF antibody disappeared or not.
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