Abstract:Abstract: Latent infection is a survival strategy of herpesvirus,despite virus infection can simulate a remarkable immune response ,the virus establishes life-long latency in ganglion ,reactivation from latency can occur after stimulus .Recently,a serial of study focus on the mechanism of latent infection and reactivation at a molecule level, However, little information is available regarding this mechanism.,which is necessary to investigate from asspects such as genome,latent infection,related protein and immune response.It will be helpful for us to know the propery of virus and search for the efficacious medicine and control programs.