Abstract:Campylobacter jejuni is a food-borne bacterial pathogen. It can produce cytolethal distending toxin, which have cell toxicity and can block the cell cycle at the G2/M boundary. Affected cells enlarge until they finally undergo programmed cell death. The toxin is composed of three subunits designated CdtA, CdtB and CdtC. This text will introduce its physicochemical properties, biological functions, mechanism of action and so on.
收稿日期: 2012-05-07
出版日期: 2013-01-07
基金资助:国家自然科学基金
通讯作者:
陆磊
E-mail: 545320981@qq.com
引用本文:
陆磊 黄金林 焦新安. 空肠弯曲菌细胞致死性肿胀毒素研究进展[J]. 中国人兽共患病学报, 2012, 28(10): 1048-1050.
Xin-An JIAO. Research progress of Campylobacter jejuni cytolethal distending toxin. Chinese Journal of Zoonoses, 2012, 28(10): 1048-1050.