Abstract：This research aims to detect the indoor allergen concentration before and after air cleaner operating and investigate the effects of it on antigen immunoreactivity as time changing. The samplers of dust mite allergens were collected through dust sampler from the four knids of environments: (1) air conditioner and air cleaner were both turned off; (2) air conditioner was runing and air cleaner was turned off; (3) air conditioner and air cleaner were both runing; (4) air conditioner was turned off and air cleaner was running. The concentrations of dust mite allergens from four kinds of environments were detected by ELISA. Dust mite allergens were treated by air cleaner in different timing points, and through ELISA and immunoblotting, the changes of dust mite allergen immune activities were determined. Results showed that the concentrations of dust mite allergens were increased in all 20 sample rooms when air conditioners were running. However, when the air cleaner was running, the concentrations of Der f 1 and Der f 2 were reduced whatever the air conditioner was operating or not (P <0.01). The immune activities of dust mite allergen were decreased because of plasma sterilization. In conclusion, the air cleaner in this study could reduce the concentrations of dust mite allergens Der f 1 and Der f 2, and also reduce the immune activities of allergens on the filters by plasma sterilization. Our results indicate that air cleaner plays an essential role in prevention of allergic disorders such as asthma and allergic rhinitis.
马忠校，刘晓宇，杨小猛，王媛媛，吴莹莹，刘志刚. 空气净化器降低室内尘螨过敏原含量及其免疫反应性的实验研究[J]. 中国人兽共患病学报, 2013, 29(2): 133-137.
MA Zhong-xiao, LIU Xiao-yu, YANG Xiao-meng, WANG Yuan-yuan, WU Ying-ying, LIU Zhi-gang. Experimental research on air cleaner’s effect in reducing the level of mites’ allergen and immunoreactivity in indoor environment. Chinese Journal of Zoonoses, 2013, 29(2): 133-137.
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