Advancement of studies on utilizing mosquito Wolbachia in field experiment
ZHANG Dong-jing1, LIANG Ge-hao2, ZHENG Zhan-tu2, LIU Xiu-ting2, HE Shi-ping2, YE Hui-zhen2, LI Zhuo-ya1, ZHAN Xi-mei1, ZHENG Xiao-ying1
1. Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University / Key Laboratory of Tropical Disease Control, Ministry of Education, Sun Yat-sen University, Guangzhou 510080, China; 2. Clinical Medical School, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
Abstract:Wolbachia can invade wild host population quickly via cytoplasmic incompatibility, which can suppress population size or interfere with RNA virus replication in their hosts. However, they have no influence on humans, animals, environment and biologic chain. More and more scientists are convinced that Wolbachia can be used to prevent dengue fever. This review is about the technical conditions of field experiment, the situation of biological safety and the existing problems and prospects by using Wolbachia.
张东京,梁格豪,郑展图,刘秀婷,何石萍,叶慧珍,李卓雅,詹希美,郑小英. 蚊虫Wolbachia 野外试验的研究进展[J]. 中国人兽共患病学报, 2013, 29(2): 183-186.
ZHANG Dong-jing, LIANG Ge-hao, ZHENG Zhan-tu, LIU Xiu-ting, HE Shi-ping, YE Hui-zhen, LI Zhuo-ya, ZHAN Xi-mei, ZHENG Xiao-ying. Advancement of studies on utilizing mosquito Wolbachia in field experiment. Chinese Journal of Zoonoses, 2013, 29(2): 183-186.
[1]WHO. Dengue and severe dengue[EB/OL]. http://www.who.int/mediacentre/factsheets/fs117/en/, 2012-09-01 [2]Werren JH, Zhang W, Guo LR. Evolution and phylogeny of Wolbachia: reproductive parasites of arthropods[J]. Proc Biol Sci, 1995, 261(1360):55-63.DOI: 10.1098/rspb.1995.0117 [3]Sinkins SP. Wolbachia and cytoplasmic incompatibility in mosquitos[J]. Insect Biochem Mol Biol, 2004, 34(7): 723-729. DOI: 10.1016/j.ibmb.2004.03.025 [4]Hoffmann AA, Montgomery BL, Popovici J, et al. Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission[J]. Nature, 2011, 476: 454-457. DOI: 10.1038/nature10356 [5]Jeffery JA, Thi Yen N, Nam VS, et al. Characterizing the Aedes aegypti population in a Vietnamese village in preparation for a Wolbachia-based mosquito control strategy to eliminate dengue[J]. PloS Negl Trop Dis, 2009, 3(11): e522. DOI:10.1371/journal.pntd.0000552 [6]Mercot H, Poinsot D. Infection by Wolbachia: from passengers to residents[J]. C R Biol, 2009, 332(2/3):284-297. DOI: 10.1016/j.crvi.2008.09.010 [7]Zug R, Hammerstein P. Still a host of hosts for Wolbachia: analysis of recent data suggests that 40% of terrestrial arthropod species are infected[J]. PLoS ONE, 2012, 7(6): e38544. DOI:10.1371/journal.pone.0038544 [8]Xi Z, Khoo CC, Dobson SL. Wolbachia establishment and invasion in an Aedes aegypti laboratory population[J]. Science, 2005, 310(5746): 326-328. DOI: 10.1126/science.1117607 [9]Ruang-areerate T, Kittayapong P. Wolbachia transinfection in Aedes aegypti: a potential gene driver of dengue vectors[J]. PNAS, 2006, 103(33): 12534-12539. DOI:10.1073/pnas.0508879103 [10]Cook PE, McMeniman CJ, O’Neil SL. Modifying insect population age structure to control vector-brone disease[J]. Adv Exp Med Biol, 2008, 627: 126-140. DOI: 10.1007/978-0-387-78225-6_11 [11]McMeniman CJ, Lane RV, Cass BN, et al. Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti[J]. Science, 2009, 323(5910): 141-144. DOI: 10.1126/science.1165326 [12]Teixeira L, Ferreira A, Ashburner M. The bacterial symbiont Wolbachia induces resistance to RNA viral infections in Drosophila melanogaster[J]. PLoS Biol, 2008, 6(12):e2. DOI:10.1371/journal.pbio.1000002 [13]Bian G, Xu Y, Lu P, et al. The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti[J]. PLoS Pathog, 2010, 6(4):e1000833. DOI:10.1371/journal.pone.0013398 [14]Moreira LA, lturbe-Ormaetxe I, Jeffery JA, et al. A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya and Plasmodium[J]. Cell, 2009, 139(7):1268-1278. DOI: 10.1016/j.cell.2009.11.042 [15]Pan X, Zhou G, Wu J, et al. Wolbachia induces reactive oxygen species (ROS)-dependent activation of the Toll pathway to control dengue virus in the mosquito Aedes aegypti[J]. Proc Natl Acad Sci U S A, 2011, 109(1): E23-31. DOI:10.1073/pnas.1116932108 [16]Frentiu FD, Robinson J, Young PR, et al. Wolbachia-mediated resistance to dengue virus infection and death at the cellular level[J]. PLoS ONE, 5(10): e13398. DOI:10.1371/journal.pone.0013398 [17]Lu P, Bian G, Pan X, et al. Wolbachia induces density-dependent inhibition to dengue virus in mosquito cells[J]. PLoS Negl Trop Dis, 2012, 6(7): e1754. DOI: 10.1371/journal.pntd.0001754 [18]Blagrove MS, Arias-Goeta C, Failloux AB, et al. Wolbachia strain wMel induces cytoplasmic incompatibility and blocks dengue transmission in Aedes albopictus[J]. Proc Natl Acad Sci U S A, 2011, 109(1): 255-260. DOI:10.1073/pnas.1112021108 [19]Walker T, Johnson PH, Moreira LA, et al. The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations[J]. Nature, 2011, 476: 450-453. DOI:10.1038/nature10355 [20]Popovici J, Moreira LA, Poinsignon A, et al. Assessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes[J]. Mem Inst Oswaldo Cruz, Rio de Janeiro, 2010, 105(8): 957-964. DOI: 10.1590/S0074-02762010000800002 [21]Moreira LA, Saig E, Turley AP, et al. Human probing behavior of Aedes aegypti when infected with a life-shortening strain of Wolbachia[J]. PLoS Negl Trop Dis, 2009b, 3(12): e568. DOI:10.1371/journal.pntd.0000568 [22]McMeniman CJ, Lane AM, Fong AW, et al. Host adaptation of a Wolbachia strain after long-term serial passage in mosquito cell lines[J]. Appl Environ Microbiol, 2008, 74: 6963-6969. DOI:10.1128/AEM.01038-08