Level of plasma D-dimer in advanced schistosomiasis patients
REN Jian-wei1, HU Fei2, LI Xiao-gang3, DING Gang4, WAN La-gen5, LI Dong2, ZHANG Lun-li5, NING An2
1.Health Division of Guard Bureau, General Staff Department of Chinese PLA, Beijing 100017, China; 2.Jiangxi Provincial Institute of Parasitic Diseases, Nanchang 330046, China; 3.Jinxian County Station of Schistosomiasis Control, Jinxian 331700, China; 4.Gao’an City Station of Schistosomiasis Control, Gao’an 330800, China; 5.The First Affiliated Hospital of Nanchang University, Nanchang 330006, China
Abstract：The advanced schistosomiasis patients, who lived in schistosomiasis endemic area of 8 counties around Poyang Lake, were considered as study subjects, and the regents of plasma D-dimer detection were used to detect concentration of D-dimer in the plasma of patients. A total of 964 advanced cases were investigated, abnormal rate of D-dimer was 51.98%, and the highest value was 5 960 μg/L. The level of D-dimer in simple and complicated case were 468.67±525.23 and 505.50±634.95, respectively, and there was a significant difference with healthy population (P<0.01). There were weak positive correlation between plasma D-dimer and grade of hepatic fibrosis (rsim=0.067, rcom=0.117, Pave<0.05). Levels of D-dimer were affected by years of sick, history of peritoneal dropsy and bleeding. It’s suggested that advanced schistosomiasis could increase level of plasma D-dimer, the variation of D-dimer could give a basis for judge the extent of advanced schistosomiasis, and the mechanism and influence factors should be further investigated.
任建伟,胡飞,李小刚,丁岗,万腊根,李东,张伦理,宁安. 晚期血吸虫病患者血浆D-二聚体水平变化及诊断价值[J]. 中国人兽共患病学报, 2013, 29(11): 1095-1098.
REN Jian-wei, HU Fei, LI Xiao-gang, DING Gang, WAN La-gen, LI Dong, ZHANG Lun-li, NING An. Level of plasma D-dimer in advanced schistosomiasis patients. Chinese Journal of Zoonoses, 2013, 29(11): 1095-1098.
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2013, Vol. 29 
