Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Diseases Prevention and Control, Ministry of Health, Center for Pesticide Effect Evaluation, Wuxi 214064, China
Abstract:As a widely used mollusicicide in the schistosomiasis endemic areas, niclosamide has played a critical role in the control of schistosomiasis in China. However, its toxicity to the non-target organisms and the impact on the ecological environment has been widely concerned. This review is mainly on the discussion of degradation and adsorption of niclosamide in the water-soil system and the metabolism in the organisms. All of these could provide the reference evidence for the ecological environment risk assessment.