1.College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China; 2.State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China; 3.College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
Abstract：Toxoplasma gondii is an obligate intracellular parasitic protozoan. There is no effective specific drug for treatment of T. gondii infection due to its complex life cycle and pathogenesis. With the increasing interests in studies of anti-T. gondii immunity and vaccines in recent years, rhoptry neck proteins (RONs) and rhoptry proteins (ROPs), as potentially important anti-T. gondii vaccine candidate antigen molecules, have been studied extensively for anti-T. gondii immunity and vaccines. This article summarizes new progresses in studies of RONs and ROPs of T. gondii in recent years, especially those regarding the potentiality of RONs and ROPs as novel DNA vaccine molecules.
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2013, Vol. 29 
