1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China; 2.Institute of Veterinary Science, the Academy of Military Medical Sciences, Changchun 130122, China; 3.Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122, China
Abstract:The occurrence of antimicrobial resistance and related resistance patterns of Escherichia coli from dogs was investigated in this study. A total of 191 anal swab samples were collected from dogs including 59 working dogs. E. coli were isolated and analyzed for phylogenetic groups and resistance to 13 antimicrobial agents. A total of 254 Escherichia coli isolates were recovered from 191 anal swab samples of dogs. Among canine E. coli isolates, 77.56% were resistance to amikacin and 75.98% to ampicillin. Resistance to meropenem and polymyxin B was observed in 3.54% and 3.94% of the isolates, respectively. Of 187 (73.62%) of 254 Escherichia coli isolates were multiple resistant (resistance to more than three kinds of antibiotics) and only 8 strains (3.15%) of E. coli did not show any resistance to all 13 antimicrobial agents. The results showed that the drug resistance rate of E. coli strains isolated from pet dogs were higher than those from working dogs. Epidemiological background and basic data of drug resistance of E. coli from dog were obtained. It was the first report that E. coli isolated from dog could resistant to 12 kinds of antibiotics, which suggested that more attention should be paid to the use of antimicrobials and the occurrence of antimicrobial resistance in companion animals. This investigation provided data on occurrence of antimicrobial resistance in E. coli from dogs, which may be useful for the small animal practitioner.
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