Investigation of Toxoplasma infection among planned pregnant women in Chongqing, China
LIU Jun, CHEN Qing, YANG Liu, HE Yang, TONG Qi
The instruction department of Population and Family Planning Science and Technology Institute,Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission ,Chongqing 400020,China
Abstract：We investigated the Toxoplasma infection prevalence among planned pregnant women in Chongqing, and to provide reference for the first level intervention of birth defects in the region. A total of 11 953 planned pregnant women were selected by proportionally stratified multi-stage random sampling method. Questionnaire survey was given to the women, and blood samples were collected. Specific IgM and IgG antibodies against Toxoplasma were detected with ELISA. Results showed that among the 11 953 cases surveyed, Toxoplasma IgM was positive in 71 cases, with the positive rate of 0.59%; IgG was positive in 771 cases, with the positive rate of 6.54%. The positive rate of IgM and IgG antibodies in the metropolitan core region of the city was higher than that in the suburb areas (χ2=35.28, P<0.000 1; χ2=82.65, P<0.000 1). The positive rate of IgM antibody increased with the educational level (χ2trend=3.25, P=0.001 1). The positive rates of IgM and IgG varied in occupations among women (χ2 =13.93, P=0.016 0; χ2 =15.58, χ2 =0.008 1), with the highest rate of public officials. Planned pregnant women with the history of abnormal pregnancy outcomes had higher positive rate of T. gondii IgM and IgG antibodies than those in the control (χ2=6.85, P=0.008 9; χ2=59.25, P<0.000 1). There was no significant difference of IgM positive rate between the planned pregnancy women who had closed contact to cats and the control group (χ2=0.23, P=0.628 6), while the positive rate of IgG was higher than that of the control group (χ2=9.95, P=0.001 6). T. gondii infection rate was on the low level of planned pregnant women in Chongqing. Adverse pregnancy outcomes are related to Toxoplasma infection.
刘俊, 陈庆, 杨柳, 何杨, 童琦. 重庆地区计划妊娠妇女弓形虫感染现况调查[J]. 中国人兽共患病学报, 2015, 31(3): 284-288.
LIU Jun, CHEN Qing, YANG Liu, HE Yang, TONG Qi. Investigation of Toxoplasma infection among planned pregnant women in Chongqing, China. Chinese Journal of Zoonoses, 2015, 31(3): 284-288.
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