Natural hosts infected with Babesia in Fujian Province, China
XIAO Fang-zhen1, LIN Dai-hua1, LIU Wei-jun1, HAN Teng-wei1, ZHOU Shu-heng1, DENG Yan-qin1,2
1. Fujian Key Laboratory for Zoonoses, Fujian Center for Disease Control and Prevention, Fuzhou 350001, China; 2. Fujian Medical University, Fuzhou 350001, China
Abstract：We explored the status of Babesia infection in natural hosts in Fujian Province. Rodents in Fujian Province were captured by the night trapping method during 2014-2016. Heart blood samples were collected. At the same time blood samples of ox, goats and dogs were also collected, from which the fragments of 18S rRNA gene of Babesia were amplified by polymerase chain reaction (PCR). Data on infection rate were analyzed with Chi-square or Fisher exact test to indicate statistical significance. Results showed that 5 917 cages were laid and 381 rodents were captured, density of rodent was 6.44%. The overall Babesia infection rate in rodents was 7.61%, while infection rate in domesticated rodents was 1.68%, and the infection rate in wide rodents was 12.87%. The infection rate was higher in wild rodents than that in domesticated rodents, and the statistical analysis result revealed a significant difference. The infection rates in region of Central Fujian and Eastern Fujian was high, and no infection was found in Southern Fujian region. The statistical analysis result revealed a significant difference in infection rate among different regions. The infection rate of goats and dogs were determined to be 1.79% and 0.55%, and no infection was found in ox. The infection rate was higher in rodents than that in other host animals, and the statistical analysis result revealed a significant difference. It is suggested that the rodents, especially the wide rodents are the main natural hosts of Babesia.
肖方震, 林代华, 刘维俊, 韩腾伟, 周淑姮, 邓艳琴. 福建省动物宿主感染巴贝虫调查研究[J]. 中国人兽共患病学报, 2017, 33(9): 789-792.
XIAO Fang-zhen, LIN Dai-hua, LIU Wei-jun, HAN Teng-wei, ZHOU Shu-heng, DENG Yan-qin. Natural hosts infected with Babesia in Fujian Province, China. Chinese Journal of Zoonoses, 2017, 33(9): 789-792.
[1] Hunfeld KP, Hildebrandt A,Gray JS. Babesiosis: recent insights into an ancient disease[J]. Int J Parasitol, 2008, 38(11): 1219-1237. doi:10.1016/j.ijpara.2008.03.001 [2] Sun JH, Han JP, Feng Z, et al. Research progress on diagnostic methods for Babesia microti infection[J]. Chin J Parasitol Parasit Dis, 2013, 31(3): 235-237. (in Chinese) 孙嘉慧,韩建平,冯正,等.田鼠巴贝虫病诊断方法的研究进展[J].中国寄生虫学与寄生虫病杂志,2013,31(3):235-237. [3] Vannier E, Krause PJ. Human babesiosis[J]. N Engl J Med, 2012, 366(25): 2397-2407. doi:10.1056/NEJMra1202018 [4] Krause PJ, Telford SR III, Spielman A, et al. Concurrent Lyme disease and babesiosis , evidence for increased severity and duration of illness[J]. J Am Med Assoc, 1996, 275(21): 1657-1660. [5] Jiang LP, Zhang L, Bao QH, et al. Babesia DNA segments detected from rodents in Zhejiang province[J]. Chin J Vector Biol Control, 2012, 23(4): 303-305. (in Chinese) 姜理平,张磊,鲍庆汉,等.浙江省在鼠类中检测到巴贝西原虫DNA片段[J].中国媒介生物学及控制杂志,2012,23(4):303-305. [6] Yao LN, Ruan W, Zeng CY, et al. Pathogen identification and clinical diagnosis for one case infected with Babesia [J]. Chin J Parasitol Parasit Dis, 2012, 30(2): 118-121.(in Chinese) 姚立农,阮卫,曾长佑,等.1例人感染巴贝虫的诊断与病原体鉴定[J].中国寄生虫学与寄生虫病杂志,2012,30(2):118-121. [7] Armstrong PM, Katavolos P, Caporale DA, et al. Diversity of Babesia infecting deer ticks ( Ixodes dammini )[J]. Am J Trop Med Hyg, 1998, 58(6): 739-742. [8] Bai HP, Sun WM, Ren Q, et al. Research progress on Babesia microti infection of China[J].Nat Sci J Harbin Normal Univ, 2014, 30(5): 100-103. (in Chinese) 白海鹏,孙维敏,任仟,等.我国巴贝虫病研究进展[J]. 哈尔滨师范大学自然科学学报,2014,30(5):100-103. [9] Vyas JM, Telford SR, Robbins GK. Treatment of refractory Babesia microti infection with atovaquone-proguanil in an HIV-infected patient: case report[J].Clin Infect Dis, 2007, 45(12): 1588-1590. doi:10.1086/523731 [10] Moritz ED,Winton CS,Tonnetti L, et al. Screening for Babesia microti in the U.S. Blood Supply[J]. N Engl J Med.2016, 375(23): 2236-2245. [11] Gubernot DM, Lucey CT, Lee KC, et al. Babesia infection through blood transfusions: reports received by the US Food and Drug Administration,1997-2007[J]. Clin Infect Dis, 2009, 48(1): 25-30. doi:10.1086/595010 [12] Brennan MB, Herwaldt BL, Kazmierczak JJ, et al. Transmission of Babesia microti parasites by solid organ transplantation[J]. Emerg Infect Dis, 2016, 22(11). doi:10.3201/eid2211.151028 [13] Xiao FZ, Peng XQ, Xu GY, et al. Investigation and genetic identification on Babesia infection in the rodents in Fujian Province[J]. Chin J Parasitol Parasit Dis, 2017, 35(1): 1-5. (in Chinese) 肖方震,彭秀卿,徐国英,等. 福建省部分地区鼠类巴贝虫感染调查与基因鉴定[J].中国寄生虫学与寄生虫病杂志,2017,35(1):1-5. [14] Cao JH, Ni QX, Zhang XH, et al. Investigation on Babesia infection in the rodents and ticks in Wenzhou City[J]. Chin Rural Health Service Administration, 2016, 36(7): 880-882. (in Chinese) 曹建海,倪庆翔,张孝和,等.温州市鼠形动物及蜱媒携带巴贝虫调查结果分析[J]. 中国农村卫生事业管理,2016,36(7):880-882.
2017, Vol. 33 
