1. College of Veterinary Medicine, Yangzhou University, Yangzhou 225002, China; 2. China Institute of Veterinary Drug Control, Beijing 100081, China; 3. Yangzhou Center for Disease Control and Prevention, Yangzhou 225001, China
Abstract：To study the transmission of Salmonella and resistance genes, 116 Salmonella isolates were tested the serotypes, antimicrobial susceptibility, resistant genes on SG1 including β-lactamase genes, and multilocus sequence typing (MLST). Results showed that Salmonella isolates from the chicken belonged to ST11 clone, S. enteritidis, and ST17 clone, S. indiana, and from the pig belonged to ST40, S. derby mostly. ST11 clone showed multidrug-resistant (MDR), resistance to ampicillin, nalidixic acid, tetracycline, and cefoperazone, mostly. ST17 clone showed resistance to nine or more kinds of antibiotics including cephalosporins and fluouoquinolones, a super-MDR clone. ST11 clone carried blaTEM-1-like highly, whereas blaOXA-1-like, blaCTX-M, blaTEM-1-like, and floR, aadA2,sul1, and aac(6')-1b were highly carried in ST17 clone, a new super-MDR clone. The antibiotic abuse and misuse in food supply chains were the main origin of MDR and super-MDR Salmonella, which were transmitted by the chains. It is significance that the control of substance abuse, especially cephalosporins and fluouoquinolones, in food supply chains.
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