Liver enzymes of 191 dengue cases with fatty liver
CUI Xin-guo1, CHEN Yi-hong2, ZHOU Hong-ning1, LIU Ai-ying2, ZHANG Li-hong2
1.Yunnan Provincial Key Laboratory of Vector-borne Disease Control and Research & Yunnan Collaborative Innovation Center for Public Health and Disease Prevention and Control; Institution of Pathogens and Vectors, Pu’er Division,Dali University; Yunnan Institution of Parasitic Diseases, Pu’er, 665000, China;; 2.The Isolation Hospital of Xishuangbanna Dai Nationality Autonomous Prefecture, Xishuangbanna 666100, China
Abstract:We explored the liver enzymes characteristics of dengue patients with fatty liver in Xishuangbanna, providing evidences for local dengue fever effective treatment program. The clinical data of 191 dengue patients with fatty liver and 191 randomized controls was retrospectively analyzed on the patients’ mainly liver enzymes indicators in Xishuangbanna Prefecture from 2013 to 2015. Results showed that the 191 cases with fatty liver, the growth rate of such as alanine aminotransferase was 84.8%, aspartate aminotransferase was 90.1%, gamma glutamyltransferase was 76.8% and bilirubin index was 20.4%, except bilirubin index, the other 3 indicators in dengue patients with fatty liver were higher than those in the control group (P<0.05). The liver injury was serious for the dengue cases with fatty liver in Xishuangbanna, of those alanine aminotransferase, aspartate aminotransferase and gamma glutamyltransferase were significantly increased. These results suggested that doctors should pay attention to above 3 enzymes changes and take related treatments immediately as soon as dengue cases with fatty liver were detected.
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