Abstract：We analyzed the clinical characteristics of paragonimiasis in children in Ningbo City, in order to provide a basis for diagnosis and treatment of this disease, and to reduce the misdiagnosis. Thirty-six children seen in ningbo women and children’s hospital from January 2010 to December 2016 with a diagnosis of paragonimiasis were studied, and the medical history,conditions of diagnosis and treatment were retrospectively analyzed. A total of 36 cases were included, and there were 20 boys and 16 girls with a mean ages of 6.6 (3.4-12) years. Among these patients, 22 lived in urban area and 14 in rural area. There were 29 cases with the history of eating raw or baked crabs, freshwater shrimp and 7 cases with the history of catching the crab or drinking raw stream water before the disease onset. The clinical symptoms varied, mainly for cough and expectoration, fever, chest tightness or pain and abdominal pain. All children had the elevated eosinophilia in peripheral blood, and the blood IgE were significantly increased in 31 cases. Paragonimiasis serum antibody detection were all positive. The chest CT showed abnormal performance in 32 cases which mainly for the pulmonary lesions and pleural effusion. And 2 cases showed the imaging findings of paragonimiasis encephalopathy in their head MRI. All patients were given praziquantel treatment after the definite diagnosis, and all were not found significant adverse reactions. The clinical manifestations of children paragonimiasis in Ningbo City were complex and diverse, the children's diet and lifestyle history should be asked in detail, at the same time, combined with peripheral blood eosinophils, IgE test results and the imaging data, made a comprehensive analysis, so as to make a early diagnosis and treatment as soon as possible, and reduce the misdiagnosis rate.
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2018, Vol. 34 
