1.The Tengchong Renmin Hospital, Tengchong 679100, China; 2 The Tengchong Center for Disease Control and Prevention, Tengchong 679100, China; 3 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China;Key Laboratory for Parasitology and Vector Biology, MOH of China, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China
Abstract:In order to understand the epidemiology characteristic and risk factors for Blastocystis hominis (B. hominis) infection, a cross-sectional study was conducted in the inpatients in a community hospital in Tengchong City, Yunnan Province. After obtaining informed consent from the subjects, stool samples were collected during July 2016 to March 2017. Polymerase chain reaction (PCR)was used to detect B. hominis. A structured questionnaire was used to record the demographic information and clinical symptoms for each subjects. 507 subjects enrolled in the study. The median age was 52 years old(95%CI:51-55) including 260 males with the median age of 53 years old (95%CI:53—55)and 247 females with median age of 51 years old(95%CI:49—54), and the detection rate of B. hominis was 9.47%(48/507,95%CI:7.13—12.44). Non-flush toilet(OR=3.248,95%CI:1.245—8.473), drinking unboiled water(OR=3.11,95%CI:1.557—6.213)and anemia(OR=2.601,95%CI:1.245—8.473)was found be relevant to B. hominis infection. No significant difference was observed between B. hominis infection and clinical symptoms such as to abdominal distension (OR=0.284,95%CI:0.067—1.199), inappetence (OR=0.762,95%CI:0.330—1.758), itchy skin(OR=0.82,95%CI:0.312—2.156) and constipation(OR=1.462,95%CI:0.621—3.419). The infection rate of B. hominis is higher in rural area than other areas. Drinking unboiled water and non-flush toilet were the main factors affecting the B. hominis infection. Improving health education knowledge and improving sanitation can reduce the B. hominis infection.
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