Progress of chikungunya virus in laboratory diagnosis
XU Pei-pei, DING Xi-xia
Laboratory of Emerging Infectious Diseases and Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China
Abstract:Chikungunya virus, the causative agent for chikungunya fever, belongs to the Togaviridae family and genus of Alphavirus. It mainly infects human through the bites of mosquitoes carrying the virus, causing chikungunya fever. It is characterized by self-limiting fever, rash, myalgia, and joint pain, in which joint pain could last for months to years leading to joint disabilities. Since chikungunya virus has the same vectors with arboviruses such as dengue virus and Zika virus, and can lead to similar clinical symptoms in the acute phase, while the treatment principles and disease outcomes are completely different among these viruses, the exact laboratory diagnosis is the key for prevention and control of chikungunya. This article reviews the progress of laboratory diagnosis for chikungunya virus in recent years.
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