Abstract:Mycoplasma pneumoniae, the smallest prokaryotic microorganism that can survive in inanimate medium, is a common human pathogen that mainly causes pneumonia and other respiratory infectious diseases by adhering to the surfaces of respiratory epithelial cells and releasing harmful substances that destroy the mucosal epithelium. The pathogenicity of M. pneumoniae is closely associated with its adhesion ability. The protein that mediates adhesion is located on a tip structure-attachment organelle, in which P1 protein, containing 1627 amino acids, has attracted attention as the main adhesion protein. Its strong antigenicity may aid in the diagnosis, prevention and treatment of M. pneumoniae. Therefore, study of P1 protein of M. pneumoniae should aid in understanding of its pathogenic mechanism and enable targeted diagnosis, treatment and prevention measures.
彭凯岚, 曾焱华. 肺炎支原体P1蛋白的研究进展[J]. 中国人兽共患病学报, 2021, 37(4): 362-367.
PENG Kai-lan, ZENG Yan-hua. Research progress on the P1 protein of Mycoplasma pneumoniae. Chinese Journal of Zoonoses, 2021, 37(4): 362-367.
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