Clinical analysis of the first Naegleria fowleri infection in Fujian Province
CHEN Bao-jian1, XIE Han-guo1, LIN Wang-hui2
1. Fujian Provincial Key Laboratory for Zoonoses Research, Fujian Provincial Center for Disease Control and Prevention, Fuzhou 350001,China; 2. Fujian Medical University Union Hospital, Fuzhou 350001,China
Abstract：We report the first case of a human Naegleria fowleri infection, together with clinical and laboratory analyses. The parasite was observed in cerebrospinal fluid (CSF) through direct saline smearing, iodine staining and microscopic examination.The PCR generated products from the CSF were sequenced for homology analysis.Large numbers of amoebic cysts were visualized in the CSF through microscopy. The CSF was subjected to BGISEQ-500 detection, which identified sequence reads uniquely corresponding to the N. fowleri genome. This is the first case report of human N. fowleri infection in Fujian Province, China. The corresponding diagnosis and treatment of primary amoebic meningoencephalitis was simultaneously analyzed.
陈宝建, 谢汉国, 林婉挥. 福建省首例纳格里阿米巴(Naegleriafowleri)感染的诊治分析[J]. 中国人兽共患病学报, 2022, 38(1): 89-92.
CHEN Bao-jian, XIE Han-guo, LIN Wang-hui. Clinical analysis of the first Naegleria fowleri infection in Fujian Province. Chinese Journal of Zoonoses, 2022, 38(1): 89-92.
2022, Vol. 38 
