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Retrospective analysis of the canine rabies background in Shanghai from 2011 to 2020 |
XIA Lu-ming, YANG Xian-chao, GONG Guo-hua, WANG Jian, LIU Jian, JU Hou-bin, WU Xiu-juan, TAO Tian-gu-sheng, YU Hui-ru, LI Kai-hang, LU Jun, LI Zeng-qiang, ZHU Xiao-ying, CHEN Wei-feng, CHANG Xiao-jing, WU Jia-wen, ZHAO Hong-jin |
Shanghai Animal Disease Prevention and Control Center, Shanghai 201103, China |
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Abstract To understand the vaccination status, antibody level and epidemic situation of canine rabies in Shanghai, and to assess the epidemic risk of canine rabies, we retrospectively analyzed serologic and pathogenic detection data on canine rabies in Shanghai from 2011 to 2020. The results showed that the average antibody qualified rate in registered canines in Shanghai was 83.8% (95%CI: 83.3%~84.3%), but the qualified rate in stray dogs was only 17.7% (95%CI: 15.8%-19.6%). Furthermore, the positivity rate of rabies virus was as high as 94.1% in events in which two or more people were injured by one dog. From the perspective of time, space and group distribution, we observed differences in the levels of rabies antibodies, but the antibody levels in stray dogs significantly differed from those in urban dogs, demonstration rural dogs and farm dogs (P<0.01). The retrospective analysis results indicated that the rabies vaccination measures for registered dogs in Shanghai are reliable and effective. Because Shanghai is a natural epidemic focus of rabies, and the stray dogs have not yet built up an effective vaccination barrier sufficient to block the viral spread in the population, substantial risk of a rabies epidemic exists in Shanghai. Further strengthening of vaccination research and capture management for stray dogs are recommended.
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Received: 21 January 2021
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Corresponding Authors:
Zhao Hong-jin,Email: zhaohongjin945@163.com
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[1] 陈溥言. 兽医传染病学[M].6版.北京:中国农业出版社,2015:77-82. [2] Yang DK, Kim HH, Cho IS.Strategies for controlling dog-mediated human rabies in Asia: Using “one Health” principles to assess control programmes for rabies[J]. Rev Sci Tech off Int,Epiz,2018,37(2):473-481. [3] 张苏华. 城市宠物与管理[J].中国比较医学杂志,2010,20(11):71-75. [4] 刘健,李鑫,卢军,等.上海市狂犬病调查与分析[J].中国动物检疫,2020,37(1):16-19. [5] 沈朝建,王幼明.兽医流行病学调查与监测抽样技术手册[M].北京:中国农业出版社,2013:22-24. [6] 王龙艳,潘秀红,沈竞影,等.上海市农村地区狂犬病暴露病例流行病学特征分析[J].中国初级卫生保健,2014,28(11):64-66. [7] 上海市卫生健康委员会.上海市法定报告传染病疫情[EB/OL].(2020-07-03)[2021-01-21]. http://wsjkw.sh.gov.cn/yqxx/20201226/32c1004d956148a1-b343bdec846d1023.html. [8] Chen Y, Tian J, Chen JL.Challenges to eliminate rabies virus infection in China by 2020[J]. Lancet Infect Dis, 2017,17(2):135-136. DOI:10.1016/s1473-3099(16)30589-8 [9] 王曲直,赵洪进,沈素芳,等.上海地区犬狂犬病防疫管理现状[J].上海市畜牧兽医通讯,2019(2):53-54. [10] Ly S, Buchy P, Heng NY, et al.Rabies situation in Cambodia[J]. PLoS Negl Trop Dis, 2009, 3(9): e511. [11] 杨来宝,肖绍坦,陈红英,等.2011-2015年上海市浦东新区狂犬病暴露特征分析[J].职业与健康,2017,33(2):190-196. [12] World Health Organization.WHO expert consultation on rabies: third report[R]. Geneva: World Health Organization Technical Report Series,2018:1-183. [13] FehIner-Gardiner C. Rabies control in North America-past, present and future[J]. Rev Sci Tech off Int Epiz, 2018,37(2):421-437. [14] 盛圆贤,赵德明.狂犬病流行态势及其防控策略的研究进展[J].中国兽医科学,2009,39(9):835-838. [15] 谭海,段晓冬,张海明,等.2014年广州市区犬狂犬病横断面调查[J].中国动物检疫,2015,32(2):15-18. [16] 谭丹,刘增再,薛爽,等. 2015-2018年湖南省长沙市城区犬狂犬病免疫效果分析[J].中国动物检疫,2019,36(10):15-19. [17] Thiptara A, Atwill ER, Kongkaew W, et al.Epidemiologic trends of rabies in domestic animals in southern Thailand, 1994-2008[J]. Am J Trop Med Hyg, 2011,85(1):138-145. [18] 章域震,杨卫红,张海林,等. “攻击性”在犬类狂犬病监测与临床诊断中的作用与价值评估[J].中国人兽共患病学报,2019,35(8):774-778. DOI:103969/j.issn.1002-2694.2019.00.143 [19] Tepsumethanon V, Wilde H, Meslin FX.Six criteria for rabies diagnosis in living dogs[J]. J Med Assoc Thai,2005,88(3):419-422. [20] Rupprecht CE.A tale of two worlds: public health management decisions in human rabies prevention[J]. Clin Infect Dis, 2004,39:281-283. |
[1] |
YANG Jing, FU Wei-jie, ZHU Fei, ZENG Xiao-xu, XIE Yun, ZHANG Heng, YAN Wen-jing, LIU Xiao-qing, CHEN Tao, WANG Da-yan, SHU Yue-long. Epidemic risk of avian influenza virus over Poyang Lake region, 2014-2015[J]. Chinese Journal of Zoonoses, 2018, 34(4): 296-300. |
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